References (Products)

Product	Catalog #	Reference
PBMCs	0500-101	“Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma,” Min Lin, et al.; Cancers 2021, 13(13), 3367; Department of Molecular Medicine, City of Hope National Medical Center, Duarte, CA, USA
ColonyGEL™ Mouse Complete Medium	1202	“R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m⁶A/PFKP/LDHB axis,” Ying Qing, et al.; Molecular Cell Volume 81, Issue 5, 4 March 2021, Pages 922-939.e9; Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
ColonyGEL™ Mouse Complete Medium	1202	“Development of a Model of the Acute and Delayed Effects of High Dose Radiation Exposure in Jackson Diversity Outbred Mice; Comparison to Inbred C57BL/6 Mice,” Andrea M. Patterson, et al.; Health Phys. 2020 Nov; 119(5): 633–646. Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
ColonyGEL™ Mouse Complete Medium	1202	“In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors,” Maximilian Richter, et. al.; Blood (2016) 128 (18): 2206–2217.
Human Cord Blood CD34+ Cells	0234-101	“MicroRNA29B induces fetal hemoglobin via inhibition of the HBG repressor protein MYB in vitro and in humanized sickle cell mice,” Qingqing Gu, et al.; Front. Med., 25 November 2022 Sec. Hematology; Department of Genetics, Genomics, and Informatics, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States
Human BM MSCs	02100	“Myeloma cells self-promote migration by regulating TAB1-driven TIMP-1 expression in mesenchymal stem cells,” Malini Rethnam BSc, et al. Biochemical and Biophysical Research Communications Volume 534, 1 January 2021, Pages 843-848; Cancer Science Institute of Singapore, National University of Singapore
MSCs	02100	“Dusquetide: Reduction in oral mucositis associated with enduring ancillary benefits in tumor resolution and decreased mortality in head and neck cancer patients,” Mahesh Kudrimoti, et al. Biotechnology Reports Volume 15, September 2017, Pages 24-26, Radiation Oncology, University of Kentucky, Lexington, KY, USA
ColonyGEL™ (NHP Complete)	1402	“Isolation of a Highly Purified HSC-enriched CD34⁺CD90⁺CD45RA⁻ Cell Subset for Allogeneic Transplantation in the Nonhuman Primate Large-animal Model,” Stefan Radtke, et al.; Transplant Direct. 2020 Aug; 6(8): e579. Fred Hutch, Seattle, WA
ColonyGEL™	1101	“Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes,” Kimberly N. Smitheman, et al. Haematologica. 2019 Jun; 104(6): 1156–1167. Epigenetics Discovery Performance Unit, Oncology R&D, GlaxoSmithKline, Collegeville, PA, USA
ColonyGEL™ Human Complete Medium w/o EPO	1103	“Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia,” Chengyin Min , et al Published: January 6, 2017 Acetylon Pharmaceuticals, Boston, MA
MNCs	02100	“3-Mercaptopyruvate sulfurtransferase disruption in dermal fibroblasts facilitates adipogenic trans-differentiation,” Elena A. Ostrakhovitch, et al; Frontiers in Bioscience Research Institute in Aging and Cancer, 16471 Scientific Way, Irvine, CA, 92618, United States
PBMCs	0500-101	“A PSMA-Targeting CD3 Bispecific Antibody Induces Antitumor Responses that Are Enhanced by 4-1BB Costimulation,” Chiu, et al Cancer Immunol Res (2020) 8 (5): 596–608.
ColonyGEL -Mouse Base Medium ColonyGEL Human Base Medium	1201 1101	"Targeting FTO suppresses cancer stem cell maintenance and immune evasion," Rui Su,^1,¹⁷ Lei Dong,^1,¹⁷ Yangchan Li,^1,^10,¹⁷ Min Gao,^1,^11,¹⁷ Li Han,^1,^2,¹⁷ Mark Wunderlich,³ Xiaolan Deng,¹ Hongzhi Li,⁴ Yue Huang,⁶ Lei Gao,^1,¹² Chenying Li,^1,¹³ Zhicong Zhao,^1,¹⁶ Sean Robinson,¹ Brandon Tan,¹ Ying Qing,¹ Xi Qin,¹ Emily Prince,¹ Jun Xie,⁴ Hanjun Qin,⁵ Wei Li,¹ Chao Shen,¹ Jie Sun,⁷ Prakash Kulkarni,⁸ Hengyou Weng,¹ Huilin Huang,¹ Zhenhua Chen,¹ Bin Zhang,^7,⁹ Xiwei Wu,⁵ Mark J. Olsen,¹⁴ Markus Müschen,^1,⁹ Guido Marcucci,^7,⁹ Ravi Salgia,⁸ Ling Li,^7,⁹ Amir T. Fathi,¹⁵ Zejuan Li,¹² James C. Mulloy,³ Minjie Wei,² David Horne,⁴ and Jianjun Chen^1,^9,^18,^* 1 Department of System Biology, Beckman Research Institute of City of Hope, Monrovia, CA USA Cancer Cell. 2020 Jul 13; 38(1): 79–96.e11.
Human Peripheral Blood MNC (PBMC)	0500	"A BCMAxCD3 bispecific T cell-engaging antibody demonstrates robust antitumor efficacy similar to that of anti-BCMA CAR T cells," DiLillo, D., Olson, K., Mohrs, K., Meagher, T.C., Bray, K., Sineshchekova, O., Starts, T., Kuhnert, J., Retter, M.W., Godin, S., Sharma, P., Delfina, F., Lin, J., Thurston, G., Kirshner, J.R., Blood Adv (2021) 5 (5): 1291-13043.
ColonyGEL™	1101	"A two-step in vivo CRISPR screen unveils pervasive RNA binding protein dependencies for leukemic stem cells and identifies ELAVL1 as a therapeutic target," Vujovic, A et al, bioRxiv June 11, 2022. Cold Spring Harbor Laboratory, Laurel Hollow, NY, USA
ColonyGEL™ (Human Base)	1101	“Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia,” Lee-Sherick, A.B. et al., Oncogene, 32(46): 5359-68, November 14, 2013. Department of Pediatrics, Division of Hematology, Oncology, and Bone Marrow Transplantation, Aurora, CO, USA.
ColonyGEL™ (Human Enriched Complete)	1104	“Unique dual targeting of thymidylate synthase and topoisomerase1 by FdUMP[10] results in high efficacy against AML and low toxicity,” Pardee, T.S. et al, Blood, 119(15): 3561-3570, April 12, 2012. Department of Internal Medicine, Section on Hematology and Oncology, Wake Forest University Health Sciences, Winston-Salem, NC.
ColonyGEL™ (Mouse Complete)	1202	“Erythroid cells generated in the absence of specific β1-integrin heterodimers accumulate reactive oxygen species at homeostasis and are unable to mount effective antioxidant defenses,” Ulyanova, T. et al, Haematologica, 98(11): 1769-1777, 2013. Dept. of Medicine, Div. of Hematology, University of Washington, Seattle, USA.
ColonyGEL™ (Human Base)	1101	“Mer receptor tyrosine kinase is a therapeutic target in pre-B-cell acute lymphoblastic leukemia,” Linger R.M et al., Blood, 122(9): 1599-609, August 29, 2013. Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
ColonyGEL™ (Mouse Base)	1201	“Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis,” Tao, L. et al., Molecular Cancer, 12(55): 1-11, June 10, 2013. Department of Orthopaedic Surgery, UC Irvine Multidisciplinary Sarcoma Center, Chao Family Comprehensive Cancer Center, University of California, Irvine, USA.
ColonyGEL™ (Mouse Base)	1201	“Dietary feeding of flavokawain A, a Kava chalcone, exhibits a satisfactory safety profile and its association with enhancement of phase II enzymes in mice,” Li, X. et al., Toxicology Reports, 1: 2-11, 2014. Department of Urology, University of California Irvine, Orange, CA.
ColonyGEL™ (Human Base)	1101	“Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia,” Brandao, L.N. et al., Blood Cancer J., 3: 1-9, January 25, 2013 (e101). Department of Pediatrics, Section of Hematology, Oncology and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
ColonyGEL™ (Mouse Complete without EPO)	1203	“LINE-1-derived poly(A) microsatellites undergo rapid shortening and create somatic and germline mosaicism in mice,” Grandi, F.C. et al., Mol Biol Evol., 30(3): 503-12, March 2013. School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA.
ColonyGEL™ (Human Base)	1101	“Pre-clinical evaluation of tyrosine kinase inhibitors for treatment of acute leukemia,” Christoph, S. et al., J Vis Exp., 79: e50720, September 18, 2013. Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO.
ColonyGEL™ (Human Base)	1101	*“UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro* and In Vivo,”** Christoph, S. et al., Mol Cancer Ther., 12(11): 2367-77, November 2013. University of Colorado Anschutz Medical Campus, Aurora, CO.
Human Bone Marrow Mononuclear Cells	0300-200	"In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors," Xiang, J. et al., Blood. 125(11): 1803-1812. March 12, 2015. Center for Molecular Immunology and Infectious Disease, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA.
Human Peripheral Blood MNC (PBMC)	0500-301	“A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys,” Smith E.J. et al., Sci Rep.: 1-12, 2015 Dec 11; 5. doi: 10.1038/srep17943. Regeneron Pharmaceuticals, Tarrytown, NY, USA.
Human Mesenchymal Stem Cells (MSC)	02100	“Mesenchymal stem cell mechanics from the attached to the suspended state,” Maloney, J.M. et al., Biophys J. 99(8): 2479-87, October 20, 2010. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, USA.
Human Mesenchymal Stem Cells (MSC)	02100	“Mechanical fluidity of fully suspended biological cells,” Maloney, J.M. et al., Biophys J., 105(8): 1767-77, October 15, 2013. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Human Mesenchymal Stem Cells (MSC)	02100	“Macromolecular crowding directs extracellular matrix organization and mesenchymal stem cell behavior,” Zeiger, A.S. et al., PLoS One, 7(5): e37904, 2012. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Human Mesenchymal Stem Cells (MSC)	02100	“Why the dish makes a difference: quantitative comparison of polystyrene culture surfaces,” Zeiger, A.S. et al., Acta Biomater., 9(7): 7354-61, 2013. Department of Materials Science & Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Human Mesenchymal Stem Cells (MSC)	02100	“Onset of heterogeneity in culture-expanded bone marrow stromal cells,” Whitfield, M.J. et al., Stem Cell Res., 11(3):1365-77, November 2013. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Human CD14+ Monocytes	0514-201	“IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes,” Veeranki, S. et al.,Plos One, 6(10): e27040, October 28, 2011. Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, USA.
Human CD19+ B Cells	0519-101	“IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes,” Veeranki, S. et al.,Plos One, 6(10): e27040, October 28, 2011. Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, USA.
Human CD14+ Monocytes	0514-101	“Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells,” Rossetto, C.C. et al., PLoS Pathog., 9(5): e1003366, May 23, 2013. The University of Nevada, Reno School of Medicine, Department of Microbiology & Immunology, Reno, Nevada, USA.
Human CD14+ Monocytes	0514-201	“Characterization of Macrophage Behavior in the Human Immunoresponse and Bone Remodeling,” Davies, J. et al., Vanderbilt University Young Scientist Publication, May 2013. Vanderbilt University.
Human CD14+ Monocytes	0514-100	“Vascular Endothelial Tight Junctions and Barrier Function Are Disrupted by 15(S)-Hydroxyeicosatetraenoic Acid Partly via Protein Kinase C{epsilon}-mediated Zona Occludens-1 Phosphorylation at Threonine 770/772,” Chattopadhyay, R. et al., J Biol Chem., 289(6):3148-63, February 7, 2014. From the Department of Physiology, University of Tennessee Health Science Center, Memphis, TN.
Human PBMCs	0500-101	"MnTE-2-PyP5+ acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics and enhance the response to chemotherapy in lymphoma cells," Melba, C. et al, Free Radic Biol Med.; 83:89-100, June 2015. Department of Pathology, University of Arizona, Tucson, AZ.
Human PBMCs	0500-101	"miR-34a Blocks Osteoporosis and Bone Metastasis by Inhibiting Osteoclastogenesis and Tgif2," Krzeszinskia, J. et al., Nature.; 512(7515): 431–435, 2014 Aug 28. The University of Texas Southwestern Medical Center, Dallas, TX.
Human PBMCs	0500-101	"Transcriptome Analysis of Kaposi's Sarcoma-Associated Herpesvirus during De Novo Primary Infection of Human B and Endothelial Cells," Purushothaman, P. et al., J Virol.; 89(6): 3093–3111, 2015 Mar 15. Department of Microbiology & Immunology, University of Nevada, Reno, School of Medicine, Center for Molecular Medicine, Reno, NV.
ColonyGEL™ (NHP Complete)	1402	"MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells," Radtke, S. et al., Exp Hematol. 2019 Feb: 70:31-41.e1. Fred Hutchinson Cancer Research Center, Seattle, WA.
Human Peripheral Blood MNC (PBMC)	0500-101	"A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer," Crawford, A. et al., Science Translational Medicine 19 June 2019: Vol. 11, Issue 497, eaau 7534. Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.

References (Products)

“In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors,” Maximilian Richter, et. al.; Blood (2016) 128 (18): 2206–2217.

“Isolation of a Highly Purified HSC-enriched CD34+CD90+CD45RA− Cell Subset for Allogeneic Transplantation in the Nonhuman Primate Large-animal Model,” Stefan Radtke, et al.; Transplant Direct. 2020 Aug; 6(8): e579. Fred Hutch, Seattle, WA

“Isolation of a Highly Purified HSC-enriched CD34⁺CD90⁺CD45RA⁻ Cell Subset for Allogeneic Transplantation in the Nonhuman Primate Large-animal Model,” Stefan Radtke, et al.; Transplant Direct. 2020 Aug; 6(8): e579. Fred Hutch, Seattle, WA