Peripheral blood mononuclear cells (PBMCs) consist of lymphocytes (T cells, B cells, and NK cells), monocytes, and dendritic cells, distinguished by the presence of a single round nuclei. Mononuclear cells are isolated from leukapheresis (Leukopaks) when high numbers of MNCs are required. Cellular subpopulations (i.e., T cells) can be further isolated from mononuclear cells using immunomagnetic separation technologies.
Mononuclear cells are important medical research tools in a multitude of areas, including immunology, infectious diseases, disease modeling, biomarker identification, and personalized medicine.
Tissue source: Leukopak
AllCells offers bulk cell isolations of important cell types from single-donor leukapheresis and bone marrow material—standard and sequential immunomagnetic separation protocols are available. Obtain large quantities of quality-controlled cells including CD34+ HSPCs, lymphocyte populations (T cells, B cells, NK cells, and monocytes), and PBMCs for a variety of research and biomedical applications. Contact us for specific donor requests and custom isolation protocols.
Obtaining bulk quantities of highly pure and viable isolated cells from a qualified vendor offers researchers the opportunity to bank cells to support experimental consistency and comparability, and streamlines laboratory workflows.