Natural killer (NK) cells are cytotoxic effectors of the innate immune system with a primary role in immunosurveillance. They are capable of mounting rapid immune responses against foreign pathogens and tumor cells. Primary CD56+ NK cells can be isolated from leukapheresis material (Leukopaks) via positive or negative immunomagnetic separation.
Scientists are working on autologous and allogeneic NK cell-based cancer immunotherapies (i.e., CAR-NK cells) to treat a variety of blood and solid tumor cancers like lymphoma, leukemia, melanoma, and breast cancer.
Tissue source: Leukopak
AllCells offers bulk cell isolations of important cell types from single-donor leukapheresis and bone marrow material—standard and sequential immunomagnetic separation protocols are available. Obtain large quantities of quality-controlled cells including CD34+ HSPCs, lymphocyte populations (T cells, B cells, NK cells, and monocytes), and PBMCs for a variety of research and biomedical applications. Contact us for specific donor requests and custom isolation protocols.
Obtaining bulk quantities of highly pure and viable isolated cells from a qualified vendor offers researchers the opportunity to bank cells to support experimental consistency and comparability, and streamlines laboratory workflows.