Blog

Sep 27 2022

Celebrating a 15 Year Milestone

Thank you for being a part of our company’s success over the years. Whether we’ve run a study for you, you’ve ordered cell products from us, or you’ve just followed ReachBio over the years, we’re.…

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Mar 08 2019

Impact of Monoclonal Antibody (MoAb), Payload and Linker Structure in Antibody Drug Conjugates (ADCs) on Primitive Myeloid Progenitors (CFU-GM), or Mature Neutrophil Cytotoxicity

 P. Ryan1, E. Clarke2, G. dos Santos2, T. Kell2, Y. Huang2, J. Borrok1, V. Balakumar3, S. Gregson3,P. Ryan1, P. Howard3, and R. Dixit1.1MedImmune LLC, Gaithersburg, MD;2ReachBio Research Labs,.…

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Nov 12 2018

Reliable and Predictive In Vitro Assays for Myelotoxicity and Cardiotoxicity of Kinase Inhibitors

Clarke E1., Schwengberg S2., Kettenhofen R2., dos Santos G1., Bohlen H2., Society of Toxicology 48th Annual Meeting & ToxExpo 2009, Poster Abstract No.1854. 1 ReachBio Research Labs, Seattle, WA,.…

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Oct 29 2018

Differential Toxicities of Kinase Inhibitors (KI) on Bone Marrow Progenitors from Different Species

Clarke E., dos Santos G., Society of Toxicology 50th Annual Meeting & ToxExpo 2010, Poster Abstract No.1172. ReachBio Research Labs, Seattle, WA.

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Oct 25 2018

ISMTR-283 Protects Human Bone Marrow Progenitors from the Lethal Effects of Ionizing Radiation

Clarke E1., Traynor-Kaplan A2., Society of Toxicology 51st Annual Meeting & ToxExpo 2012, Poster Abstract No.218. 1ReachBio, Seattle, WA, 2ISM Therapeutics, Seattle, WA.

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Oct 22 2018

Effects of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors on Platelet Development

Singh J1., Zabka T1., Uppal H1,. Tarrant J1., Clarke E2., Lin T1., McCray B1., La N1., Nguyen T1., Dhawan P1., Doudement E1., Kauss A1., Dambach D1., Misner D1., Society of Toxicology 52nd Annual.…

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Oct 18 2018

Effects of Tyrosine Kinase 2 Inhibitors on Megakaryocyte Development

Uppal H1., Danilenko D1., Harstadt E1., Tarrant J1., Clarke E2., Dhawan P1., Kauss A1., McCray B1., Misner D1., Singh J1., Society of Toxicology 52nd Annual Meeting & ToxExpo 2013, Poster Abstract.…

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Oct 15 2018

Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutropenia with Combination Therapies

dos Santos G., Mergaert A., Clarke E., Society of Toxicology 52nd Annual Meeting & ToxExpo 2013, Poster Abstract No.1198. ReachBio , Seattle, WA.

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Oct 11 2018

An Ex Vivo Platform to Evaluate the Differential Effects of Potential Therapies on Leukemia Progenitors (CFU-L) vs Normal Bone Marrow Progenitors (CFU-GM)

Clarke E., Kyriss B., Mergaert A., Society of Toxicology 53rd Annual Meeting & ToxExpo 2014, Poster Abstract No.1920. ReachBio Research Labs, Seattle, WA.

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Oct 08 2018

3 Methods for Evaluating Cytokine Storm Risk

dos Santos G., Clarke E., Society of Toxicology 53rd Annual Meeting & ToxExpo 2014, Poster Abstract No.270. ReachBio Research Labs, Seattle, WA.

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